VIP 10mg

Vasoactive Intestinal Peptide (VIP) is a naturally occurring 28-amino-acid neuropeptide belonging to the secretin/glucagon superfamily. Distributed throughout the central nervous system, gastrointestinal tract, and immune tissue, it signals through the VPAC1 and VPAC2 receptors. Research has focused on immune modulation, circadian rhythm, vasodilation, and pulmonary function.

Chemical Makeup Molecular Formula: C147H238N44O42S | Molecular Weight: approximately 3326.8 g/mol | Also known as: Vasoactive Intestinal Peptide, Aviptadil (synthetic form)

Research Highlights

• Immune Modulation — Research suggests VIP may shift immune responses toward an anti-inflammatory profile, influencing regulatory T cell populations and reducing pro-inflammatory cytokine expression.
• Circadian Signaling — Studies of the suprachiasmatic nucleus indicate VIP acts as a synchronizing signal between clock neurons, with VIP-deficient models showing disrupted circadian rhythms.
• Vasodilation — Research describes potent smooth muscle relaxation and vasodilatory activity, particularly within pulmonary and systemic vasculature.
• Pulmonary Research — Synthetic VIP has been investigated in models of respiratory injury, with attention to protection of alveolar type II cells.
• Neuroprotection — Studies suggest VIP may support neuronal survival and influence neurotrophic signaling in developmental models.

Available for research and laboratory purposes only.