BPC-157 10mg

BPC-157 (Body Protection Compound-157)

BPC-157, also known as Pentadecapeptide BPC-157 or Body Protection Compound-157, is a synthetic 15-amino acid peptide derived from a protein found in gastric juice. Extensively researched for its potential in tissue repair and regeneration, it appears to work by binding to growth hormone receptors, stimulating cell proliferation, promoting collagen development, and inducing angiogenesis. Research has expanded to cover gastrointestinal healing, tendon and muscle repair, neurological protection, and dopamine system modulation.

Chemical Makeup Molecular Formula: C62H98N16O22 | Molecular Weight: 1419.55 g/mol | Also known as: Body Protection Compound-157, Pentadecapeptide BPC-157

Research Highlights

• Wound Healing — Murine studies across multiple wound types found BPC-157-exposed models exhibited significantly higher collagen, reticulin, and blood vessel formation vs. controls. Research also suggests the peptide may enhance VEGF expression, promote endothelial cell proliferation and migration, and regulate ERK1/2 phosphorylation — key drivers of angiogenesis and tissue repair.
• Tendon Healing — Studies in cultured tendon fibroblasts found BPC-157 may promote outgrowth, enhance cell survival under oxidative stress, increase migration, and activate the FAK-paxillin pathway — suggesting a role in cytoskeletal organization and tendon regeneration rather than simply increasing protein production.
• Gastrointestinal Healing — Among angiogenic growth factors studied, BPC-157 was the only compound showing consistent healing results across all GI wound types — including esophagus, stomach, duodenum, and lower GI tract — in both acute and chronic conditions.
• Muscle Healing — In corticosteroid-induced muscle damage models, BPC-157 appeared to produce complete restoration of gastrocnemius muscle function and healing ability within 14 days, while the placebo group showed no apparent recovery.
• Tissue Damage & Organ Protection — Research suggests BPC-157 may exert broad protective action across multiple organ systems — including the pancreas, liver, heart, and endothelium — potentially via peptidergic defense mechanisms that counteract dopamine, nitric oxide, prostaglandin, and somatosensory neuron system dysregulation.
• Central Nervous System — In traumatic brain injury murine models, BPC-157 appeared to reduce mortality, limit severity of subarachnoid and intraventricular hemorrhage, decrease brain edema, and show potential preventive effects when introduced prior to injury.
• Dopamine System — Studies in amphetamine-treated murine models found BPC-157 appeared to reverse amphetamine-induced excitability and produced near-complete reversal of haloperidol action, suggesting meaningful interaction with the dopaminergic system.

Available for research and laboratory purposes only.